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Cat. No. Product Name Information
PC-23158

AN-329

Hsp110 inhibitor

AN-329/43448068 (AN-329) is a small molecule inhibitor of Hsp110-STAT3 association, effectively inhibits HPAECs proliferation with IC50 of 22.67 uM, binds to bind to Hsp110 with KD of 12.6 uM.
PC-21234

XL888

HSP90 inhibitor

XL888 is a potent small molecule inhibitor of HSP90 with IC50 of 24 nM, inhibits cell proliferation of multiple cancer cell types.
PC-20807

HLQ2H

Hsp110-STAT3 inhibitor, Msi3 inhibitor

HLQ2H (Msi3 inhibitor 2H) is a first-in-class, specific inhibitor of fungal Hsp110 molecular chaperone Msi3, inhibits the holdase activity of Msi3 (IC50=5.02 uM) as well as the growth and viability of C. albicans.
PC-20710

STA-9090

HSP90 inhibitor

Ganetespib (STA 9090) is a potent, second generation small-molecule inhibitor of HSP90 (IC50=4 nM).
PC-20709

STA-1474

HSP90 inhibitor

STA-1474 is a water soluble prodrug of Ganetespib (STA 9090), which is a potent, second generation small-molecule inhibitor of HSP90 (IC50=4 nM).
PC-49868

Debio 0932

HSP90 inhibitor

Debio 0932 (CUDC-305, RGRN-305) is a highly potent, oral and BBB-penetrant HSP90 inhibitor, shows high affinity for HSP90alpha/beta and HSP90 complex derived from cancer cells with IC50 of 100 nM and 48.8 nM, respectively.
PC-49842

PST inhibitor peptide-8

Pancreastatin inhibitor

PST inhibitor peptide-8 (PSTi8) is a potent pancreastatin (PST) inhibitor, competes with PST on GRP78 receptor binding and rescues PST-induced insulin resistance (IR) both in vitro and in vivo.
PC-49775

KUNG65

Grp94 inhibitor

KUNG65 is a potent, selective glucose regulated protein 94 (Grp94) inhibitor with Kd value of 540 nM in fluorescence polarization assays, 73-fold selectivity over Hsp90α.
PC-49670

VER-50589

Hsp90 inhibitor

VER-50589 (VER50589) is a potent, selective small-molecule inhibitor of Hsp90 with IC50 of 21 nM and Kd value of 4.5 nM.
PC-49669

VER-49009

Hsp90 inhibitor

VER-49009 (CCT0129397, VER49009) is a potent, selective small-molecule inhibitor of Hsp90 with IC50 of 25 nM and Kd value of 78 nM, inhibits ATPase activity of full length yeast Hsp90 protein with IC50 of 0.14 uM.
PC-49601

Grp78 inhibitor 8

Grp78 inhibitor

Grp78 inhibitor 8 is a potent, isoform-selective inhibitor of the ER Resident Chaperone Grp78 (HSPA5) with IC50 of 0.59 uM.
PC-49317

PLTFBH

DNAJA1 inhibitor

PLTFBH is a cell-active small molecule inhibitor of DNAJA1, binds to and reduces protein levels of DNAJA1 and several other HSP40/J-domain proteins (JDPs), specifically reduces conformational mutp53 levels similar to PLIHZ.

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