| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35350 |
SKL2001
|
909089-13-0 |
SKL2001 is a specific small molecule activator (agonist) of the Wnt/β-catenin pathway, stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction. |
| PC-35329 |
E-7386
|
1799824-08-0 |
E-7386 (E7386) is a potent, orally active modulator of CBP/beta-catenin, disrupts the interaction and inhibits canonical Wnt signaling pathway /TCF reporter gene activity in LiCl-stimulated HEK-293 and MDA-MB-231 with IC50 of 55 and 73 nM, respectively. |
| PC-61323 |
Carnosic acid
|
3650-09-7 |
Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM. |
| PC-61288 |
Tegatrabetan
|
1227637-23-1 |
Tegatrabetan (BC-2059, BC2059, Tegavivint) is an orally bioavailable β-catenin antagonist that disrupts the binding of β-catenin to TBL1 and promotes β-catenin degradation, attenuates nuclear and cytoplasmic levels of β-catenin. |
| PC-70120 |
PRI-724
|
847591-62-2 |
PRI-724 (PRI724) is a potent, specific, second generation CBP/beta-catenin antagonist with IC50 of 150 nM, an isomer or enantiomer of ICG-001. |
| PC-70092 |
KYA-1797K
|
1956356-56-1 |
KYA-1797K is a derivative of KY1220 with improved inhibitory activity for Wnt/β-catenin signaling. |
| PC-70091 |
KY-1220
|
292168-79-7 |
KY-1220 is a small molecule destabilizer of both β-catenin and Ras via inhibition of the Wnt/β-catenin pathway (IC50=2.1 uM). |
