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Cat. No. Product Name CAS No. Information

(R)-DRF053 dihydrochloride

1241675-76-2 (R)-DRF053 dihydrochloride (DRF053) is a potent, cell-permeable, dual CK1/CDK inhibitor with IC50 of 14 nM, 220 nM and 80 nM for CK1, CDK5/p25 and CDK1/cyclin B, respectively.


1242422-09-8 SSTC3 is a novel small-molecule CK1α activator with EC50 of 30 nM (WNT-driven reporter gene assay), Kd of 32 nM.


1415921-09-3 VU-WS113 is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity.


1009820-21-6 CX-4945 (Silmitasertib, CX4945) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase Casein Kinase 2 (CK2) with Ki of 0.38 nM, CK2α IC50 of 1 nM.


301836-43-1 D4476 (Casein Kinase I Inhibitor, D 4476, D-4476) is a potent, selective ATP-competitive inhibitor of CK1 with IC50 of 0.3 uM in vitro.


1454585-06-8 SR-3029 is a potent, highly selective, ATP-competitive and brain penetrating Casein Kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 44/260 nM, respectively.

Epiblastin A

16470-02-3 Epiblastin A is a small molecule ATP-competitive casein kinases 1 (CK1) inhibitor with IC50 values of 0.8, 3.7 and 3.8 uM for CK1δ, CK1ε and CK1α, engages CK1 isoenzymes in cell lysate and induces efficient conversion of mouse epiblast stem cells (EpiSCs) to embryonic stem cells (cESCs).

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