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Cat. No. Product Name CAS No. Information
PC-38435

3JC48-3

1629989-75-8 3JC48-3 is a potent, cellularly active and stable c-Myc inhibitor, inhibits c-Myc-max dimerization with IC50 of 34 uM, 5 times more potent than 10074-G5, exhibits an approximate twofold selectivity for c-Myc-Max heterodimers over Max-Max homodimers.
PC-35303

MYCMI-6

681282-09-7 MYCMI-6 (NSC354961) is a selective, high affinity inhibitor of MYC-MAX interaction, blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with Kd of 1.6 uM in SPR assay.
PC-60543

CBL0137

1197996-80-7 CBL0137 (Curaxin CBL0137) is a histone chaperone FACT (facilitates chromatin transcription) and MYC signal inhibitor that markedly reduced tumor initiation and progression in vivo.
PC-60241

sAJM-589

2089-82-9 sAJM-589 is a novel, potent small molecule Myc inhibitor that disrupts the Myc-Max leucine-zipper heterodimer with IC50 of 1.8 uM.
PC-49220

VPC-70063

13571-44-3 VPC-70063 (VPC70063) is a small molecule Myc inhibitor that inhibits Myc-Max transcriptional activity with IC50 of 8.9 uM in c-Myc luciferase reporter assay in LNCaP cells, disrupts the interaction of Myc-Max with DNA.
PC-38695

MYRA-B

307326-46-1 MYRA-B (NSC45641) is a small molecule that induces Myc-dependent apoptosis without affecting Myc transactivation or Myc/Max DNA binding.
PC-38694

MYRA-A

3900-43-4 MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF.

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