| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-45580 |
Caficrestat
|
1355612-71-3 |
AT-001 (Caficrestat) is a highly potent, selective inhibitor of aldose reductase enzymatic activity with IC50 of 28.9 pM. |
| PC-20086 |
BAY1128688
|
1428988-21-9 |
BAY1128688 is a potent, steroidal aldo-keto reductase 1C3 (AKR1C3) inhibitor with potential for endometriosis. |
| PC-38679 |
Govorestat
|
2170729-29-8 |
Govorestat (AT-007) is a potent, selective, CNS-penetrant aldose reductase (aldehyde reductase) inhibitor with IC50 of 0.1 nM, reduces toxic galactitol levels and prevents galactosemia disease complications in vivo. |
| PC-62883 |
MK-204
|
1959605-73-2 |
MK-204 is a potent, selective AKR1B10 inhibitor with IC50 of 80 nM, shows high selective (270-fold) over AKR1B1. |
| PC-62882 |
IDD388
|
314297-26-2 |
IDD388 is a potent aldose reductase (ALR2 or AKR1B1) inhibitor with IC50 of 0.4 uM, shows weak inhibition for AKR1B10 (IC50=4.4 uM).. |
| PC-61992 |
Fidarestat
|
136087-85-9 |
Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.. |
| PC-45922 |
Epalrestat
|
82159-09-9 |
A noncompetitive and reversible aldose reductase inhibitor with IC50 of 10 nM and 26 nM for purified aldose reductase from rat lens and human placenta, respectively. |
