Cat. No. |
Product Name |
CAS No. |
Information |
PC-72904 |
AMG650
|
2410796-79-9 |
AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A for treatment of advanced solid tumors. |
PC-63578 |
Kif15-IN-1
|
672926-32-8 |
Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.. |
PC-45861 |
Ispinesib
|
336113-53-2 |
Ispinesib (SB-715992) is a potent, selective, cell-permeable, allosteric inhibitor of Eg5 (mitotic kinesin KSP) with Ki of 2.3 nM. |
PC-49614 |
AM-5308
|
2410796-89-1 |
AM-5308 is a potent mitotic kinesin KIF18A inhibitor. |
PC-49285 |
BTB-1
|
86030-08-2 |
BTB-1 (KIF18A inhibitor BTB-1) is a selective and ATP-competitive mitotic kinesin KIF18A inhibitor, BTB-1 potently inhibits the ATPase activity of Kif18A with IC50 of 1.69 uM, does not inhibit other mitotic kinesins. |
PC-73188 |
Filanesib
|
885060-09-3 |
Filanesib (ARRY-520) is a potent, selective and noncompetitive kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM. |
PC-72726 |
Azo-EMD
|
|
Azo-EMD is a cell permeable, photoswitchable compound that inhibits mitotic kinesin Eg5 more potently in its light-induced cis form, used for optical control mitosis. |