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Cat. No. Product Name Information
PC-63549

Lopixibat chloride

IBAT inhibitor

Lopixibat chloride (LUM-001, HP-625) is a potent, selectiove, oral inhibitor of sodium bile acid cotransporter and Ileal bile acid transporter (IBAT)..
PC-63453

A4250

IBAT inhibitor

A4250 (A-4250, Odevixibat) is a small molecule ileal bile acid transporter (IBAT) inhibitor for the treatment of cholestatic liver diseases including progressive familial intrahepatic cholestasis and NASH..
PC-61418

Volixibat

ASBT inhibitor

Volixibat (SHP-626;SAR-548304;LUM-002) is a highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).
PC-61407

Elobixibat

IBAT inhibitor

Elobixibat (A3309, AZD7806, AJG-533) is an orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor with IC50 of 0.53 nM, 0.13 nM, and 5.8 nM for human, mouse, and canine IBAT respectively.
PC-61384

Linerixibat

ASBT inhibitor

Linerixibat (GSK2330672) is a highly potent, selective, ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor with IC50 of 2.1/1.9 nM for mouse/rat ASBT, respectively.
PC-20411

A3907

ASBT inhibitor

A3907 is an apical sodium-dependent bile acid transporter (ASBT) inhibitor.
PC-61419

Volixibat potassium

A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH)..

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