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Cat. No. Product Name CAS No. Information
PC-73316

CFT8634

2704617-95-6 CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 BiDAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.
PC-72782

GSK215

2743427-26-9 GSK215 is a potent, selective, FAK-degrading Proteolysis Targeting Chimera (PROTAC) based on a binder for the VHL E3 ligase and the known FAK inhibitor VS-4718.
PC-72621

ARV-471

2229711-68-4 ARV-471 (ARV471) is an investigational orally bioavailable PROTAC protein degrader designed to specifically target and degrade the estrogen receptor (ER) with DC50 of 1.8 nM.
PC-38054

DT2216

2365172-42-3 DT2216 (DT-2216) is a specific BCL-XL PROTAC by linking ABT263 to a VHL ligand (VHL-L), induces BCL-XL degradation in MOLT-4 T-ALL cells with DC50 of 63 nM.
PC-60126

dBRD9

2170679-45-3 dBRD9 is a potent and selective degrader (PROTAC) of BRD9 with IC50 of 56.6 nM in MOLM-13 cells.
PC-49151

QA-68-ZU81

QA-68-ZU81 (QA-68) is a EA-89-based BRD9 degrader that incorporates the EA-89 warhead into a cereblon (CRBN)-targeting proteolysis-targeting chimera (PROTAC).
PC-49144

SJ1008030

SJ1008030 is a potent, specific JAK2-degrading, GSPT1-sparing PROTAC.

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