| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-49392 |
UBX-382
|
2884554-45-2 |
UBX-382 (UBX382) is a potent and orally available proteolysis-targeting chimera (PROTAC) that induces potent BTK degradation in DLBCL cell line with DC50 of 4.5 nM. |
| PC-73321 |
CFT7455
|
2504233-68-3 |
Cemsidomide (CFT7455) is a highly potent and selective degarder of IKZF1/3 with cereblon binding IC50 of 0.4 nM and picomolar DC50. |
| PC-73316 |
CFT8634
|
2704617-95-6 |
CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 BiDAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7. |
| PC-73152 |
ACBI1
|
2375564-55-7 |
ACBI1 is a potent and cooperative degrader (PROTAC) of BAF ATPase subunits SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM, respectively. |
| PC-72782 |
GSK215
|
2743427-26-9 |
GSK215 is a potent, selective, FAK-degrading Proteolysis Targeting Chimera (PROTAC) based on a binder for the VHL E3 ligase and the known FAK inhibitor VS-4718. |
| PC-72621 |
ARV-471
|
2229711-68-4 |
ARV-471 (ARV471) is an investigational orally bioavailable PROTAC protein degrader designed to specifically target and degrade the estrogen receptor (ER) with DC50 of 1.8 nM. |
| PC-72572 |
SR-1114
|
2769141-82-2 |
SR-1114 (SR1114) is a first-in-class ENL PROTAC degarder based on SR-0813 that binds to the E3 substrate adapter cereblon (CRBN), elicits rapid CRBN-dependent degradation of ENL with DC50 of 150 nM in MV4;11 cells. |
