| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35492 |
HS56
|
922050-57-5 |
HS56 (Pim-DAPK3 inhibitor HS56) is a potent, dual Pim/DAPK3 inhibitor with Ki of 72 nM (Pim-3) and 315 nM (DAPK3), shows micromolar potency toward Pim-1 and Pim-2 (Ki=1.5 and 17 uM). |
| PC-63507 |
SEL24-B489
|
1616359-00-2 |
SEL24-B489 (SEL24, MEN1703) is a potent, dual PIM and FLT3-ITD inhibitor with Kd of 2/2/3 nM for PIM1/2/3, Kd of 160/16 nM for FLT3-WT/FLT3-ITD, respectively. |
| PC-63142 |
JP-11646
|
1902983-63-4 |
JP-11646 is a novel potent, selective, non-ATP competitive Pim2 inhibitor with IC50 of 0.5/1/24 nM for Pim2/3/1, respectively. |
| PC-70113 |
LGB-321
|
1210416-93-5 |
LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively. |
| PC-45110 |
GDC-0339
|
1428569-85-0 |
GDC-0339 (GDC0339) is a novel small molecule pan-Pim kinase inhibitor that was discovered as a potential treatment for multiple myeloma. |
| PC-45605 |
PIM-447
|
1210608-43-7 |
A highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively. |
| PC-38740 |
pan-PIM inhibitor 27
|
2698319-19-4 |
pan-PIM inhibitor 27 (SARxxxx92) is a potent, selective, orally bioavailable pan-PIM kinase inhibitor with IC50 of 1, 6 nM for Pim1 and Pim2, respectively. |
