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Cat. No. Product Name CAS No. Information


2204290-85-5 FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand.

SRI 37892

1030769-75-5 SRI 37892 (SRI37892) is a novel potent, small molecule Frizzled 7 (Fzd 7) inhibitor with IC50 of 0.66 uM in Wnt/β-catenin assay.

Compound 3235-0367

1397006-01-7 Compounmd 3235-0367 is a small-molecule inhibitor of FZD8 with IC50 of 7.1 uM against mouse FZD8 cysteine-rich domain (CRD) by cell-based assays and KD of 2.5 uM inb BLI assays, inhibits Wnt3a-induced β-catenin signaling.

Frizzled6 agonist SAG1.3

364590-63-6 Frizzled6 agonist SAG1.3 is a small molecule SMO agonist that targets Frizzled6 (FZD6) as a partial agonist with limited subtype selectivity.

Peptide Fz7-21

Peptide Fz7-21 is a potent, selective peptide inhibitor of Frizzled 7 receptor, inhibits exogenous WNT3A stimulated Wnt-β-catenin signaling in HEK293 cells with IC50 of 100 nM.


1680196-54-6 A negative allosteric modulator of the Frizzled4 (Fzd4) receptor and a Wnt/β-catenin pathway inhibitor with pEC50 value of 5.74 for inhibition of Wnt antagonism.


150068-95-4 A novel small molecule Wnt signaling inhibitor that targets the cysteine-rich domain of Frizzled, specifically binds to the Wnt binding site on the Frizzled8 cysteine-rich domain with Kd of 2.9 uM, IC50 of 5.7 uM..

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