| Cat. No. |
Product Name |
Information |
| PC-49191 |
SARS-CoV-2 PLpro inhibitor 7
|
SARS-CoV-2 PLpro inhibitor 7 is a potent, selective and covalent inhibitor of SARS-CoV-2 papain-like protease (PLpro) with IC50 of 94 nM, shows SARS-CoV-2 antiviral activity with EC50 of 1.1 uM. |
| PC-49140 |
JMX0286
|
JMX0286 is a potent, specific and allosteric inhibitor against SARS-CoV-2 3CLpro with IC50 of 4.8 uM in FRET based screening assays, shows strong inhibition of SARS-CoV-2 virus with EC50 of 2.25 uM in A549-hACE2 cells. |
| PC-49052 |
Z8539_0072
|
Z8539_0072 is a potent SARS-CoV-2 macrodomain inhibitor that binds to the NSP3 macrodomain of SARS-CoV-2 (Mac1) with IC50 of 460 nM. |
| PC-47067 |
RI173
|
RI173 is a potent, covalent, triple-acting inhibitor of SARS-CoV-2 protease Mpro, PLpro and human cathepsin L with IC50 of 0.6 uM, 0.2 uM and 1.7 uM, respectively. |
| PC-38498 |
SARS-CoV-2 nsp14 inhibitor 25
|
SARS-CoV-2 nsp14 inhibitor 25 is a highly potent, selective, nucleoside-derived inhibitor of SARS-CoV-2 nsp14 (N7-guanine)-methyltransferase (N7-MTase) with IC50 of 19 nM, no inhibition against human RNA N7-MTase (hRNMT, IC50>50 uM). |
| PC-38459 |
GS-621763
|
GS-621763 is an oral prodrug of remdesivir parent nucleoside GS-441524, inhibits SARS-CoV-2, including variants of concern in cell culture (EC50=0.11 to 0.73 uM) and human airway epithelium organoids. |
| PC-73341 |
Coronastat
|
Coranastat (NK01-63) is a GC376 analog with improved potency, and highly potent, selective SARS-CoV-2 3CL protease inhibitor with IC50 of 16 nM, exhibits antiviral potency with EC50 of 6 nM in Huh-7ACE2 cellular assays. |
