Cat. No. |
Product Name |
Information |
PC-49846 |
YL5084
JNK2/3 inhibitor
|
YL5084 (YL 5084) is a potent, selective and covalent JNK2/3 inhibitor with IC50 of 70 nM (JNK2), displays selectivity (>30-fold) for JNK2 over JNK1. |
PC-73183 |
Bentamapimod
JNK inhibitor
|
Bentamapimod (AS602801) is a potent, selective, ATP-competitive JNK inhibitor with IC50 of 80/90/230 nM for JNK1/2/3, repectively. |
PC-43490 |
JNK-IN-8
JNK inhibitor
|
JNK-IN-8 (JNK Inhibitor XVI) is a potent, selective, pan-JNK inhibitor with IC50 of 4.7 nM, 18.7 nM and 1 nM for JNK1, JNK2 and JNK3, respectively. |
PC-43332 |
CC-401 hydrochloride
JNK inhibitor
|
CC-401 hydrochloride is a potent, selective, ATP-competitive pan-JNK inhibitor with Ki of 25-50 nM, displays >40-fold selectivity over other related kinases, including p38, ERK, IKK2, PK C, Lck, and ZAP70. |
PC-43238 |
SR-3306
JNK inhibitor
|
SR-3306 (SR3306) is a highly selective, brain penetrant, potent inhibitor of JNK with IC50 of 67, 283 and 159 nM for JNK1, JNK2 and JNK3, >100-fold selectivity over p38. |
PC-63199 |
CC-401
JNK inhibitor
|
CC-401 (JNK-401) is a potent, selective, ATP-competitive pan-JNK inhibitor with Ki of 25-50 nM, displays >40-fold selectivity over other related kinases. |
PC-42856 |
SP600125
JNK inhibitor, NQO1 inhibitor
|
SP600125 is a potent, selective, reversible, ATP-competitive inhibitor of JNK with IC50 of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. |
PC-42552 |
BI-78D3
JNK inhibitor
|
BI-78D3 is a small molecule JIP1 mimic that functions as substrate competitive inhibitor of JNK with IC50 of 500 nM. |
PC-42095 |
IQ-1S
JNK inhibitor
|
IQ-1S is a potent, highly specific JNK inhibitor with IC50 of 390, 360, and 87 nM for JNK1, JNK2, and JNK3, respectively. |
PC-42785 |
AS601245
JNK inhibitor
|
AS601245 is a potent and selective inhibitor of JNK with IC50s of 70/220/150 nM for JNK1/2/3 respectively. |
PC-47480 |
AM-111
JNK inhibitor
|
Brimapitide (KU002, D-JNKI-1, XG-102, AM-111) is a cell-permeable peptide inhibitor of JNK kinases. |
PC-23102 |
JNK3 inhibitor JC16I
JNK3 inhibitor
|
JNK3 inhibitor JC16I is a potent, selective covalent JNK3 inhibitor with IC50 of 5.31 nM, >160-fold selectivity for JNK3 over JNK1/2. |