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Cat. No. Product Name CAS No. Information
PC-35427

GS-444217

1262041-49-5 GS-444217 (GS444217) is a potent, selective, ATP-competitive, orally available inhibitor of ASK1 with Kd/IC50 of 4.1/2.87 nM.
PC-62728

SW-083688

422281-45-6 SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM.
PC-60150

ASK1-IN-19

2089638-10-6 AKS1-IN-19 is a novel potent, selective and orally active ASK1 (MAP3K5) inhibitor with pIC50 of 8.3.
PC-60092

GNE-8505

1620574-24-4 GNE-8505 (GNE8505) is a potent, selective and CNS-penetrant inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM.
PC-45794

Tpl2-IN-34

915363-56-3 A potent, selective Tpl2 (cot/MAP3K8) inhibitor with IC50 of 1.6 nM.
PC-45565

Selonsertib

1448428-04-3 Selonsertib (GS-4997) is a highly selective and potent, ATP-competetive inhibitor of ASK1 (Apoptosis Signal-regulating Kinase 1, MAP3K5) with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
PC-49571

DLK-LZK inhibitor 64

DLK-LZK inhibitor 64 (example 64) is a potent, selective dual leucine zipper kinase (DLK, MAP3K12) and leucine zipper-bearing kinase (LZK) inhibitor with IC50 of 2 nM and 10 nM, respectively.

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