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Cat. No. Product Name CAS No. Information
PC-36005

2BAct

2143542-28-1 2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays.
PC-35083

Metarrestin

1443414-10-5 Metarrestin (ML246) is a specific inhibitor of perinuclear compartment (PNC), disrupts PNCs in PC3M-GFP-PTB cells with IC50 of 0.39 uM, specifically binds eEF1A2.
PC-61019

eIF4A3 inhibitor 53a

2095486-67-0 eIF4A3 inhibitor 53a is a potent, selective and cell-active eukaryotic initiation factor 4A3 (eIF4A3) inhibitor with IC50 of 0.26 uM, SPR Kd of 43 nM.
PC-70180

A-484954

142557-61-7 A-484954 (A484954) is a highly selective, small molecule eEF2K inhibitor with IC50 of 0.28 uM.
PC-45650

SBI-0640756

1821280-29-8 SBI-0640756 (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.
PC-45737

4EGI-1

315706-13-9 4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E).
PC-72482

Rohinitib

1139253-73-8 Rohinitib is a potent and specific inhibitor of eIF4A1, inhibits growth and survival of AML cells especially cells with FLT3-ITD.

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