Cat. No. |
Product Name |
CAS No. |
Information |
PC-72234 |
EGPI-1
|
2355263-33-9 |
EGPI-1 is a potent small molecule that inhibits the translation initiation factors eIF4E/eIF4G interaction. |
PC-36005 |
2BAct
|
2143542-28-1 |
2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
PC-35083 |
Metarrestin
|
1443414-10-5 |
Metarrestin (ML246) is a specific inhibitor of perinuclear compartment (PNC), disrupts PNCs in PC3M-GFP-PTB cells with IC50 of 0.39 uM, specifically binds eEF1A2. |
PC-61019 |
eIF4A3 inhibitor 53a
|
2095486-67-0 |
eIF4A3 inhibitor 53a is a potent, selective and cell-active eukaryotic initiation factor 4A3 (eIF4A3) inhibitor with IC50 of 0.26 uM, SPR Kd of 43 nM. |
PC-70180 |
A-484954
|
142557-61-7 |
A-484954 (A484954) is a highly selective, small molecule eEF2K inhibitor with IC50 of 0.28 uM. |
PC-45650 |
SBI-0640756
|
1821280-29-8 |
SBI-0640756 (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. |
PC-45737 |
4EGI-1
|
315706-13-9 |
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E). |