| Cat. No. |
Product Name |
Information |
| PC-72232 |
DS12881479
|
DS12881479 (DS 12881479) is a novel potent, selective inhibitor of MAPK-interacting kinase 1 (Mnk1) with IC50 of 21 nM, stabilizes the autoinhibited state of Mnk1. |
| PC-63366 |
ETC-206
|
ETC-206 (ETC-1907206) is a novel potent, selective MNK1/2 inhibitor with IC50 of 64/86 nM, inhibits eIF4E phosphorylation inhibition in HeLa cell line with IC50 of 321 nM. |
| PC-62896 |
BAY 1143269
|
BAY 1143269 is a potent, selective, orally bioavailable inhibitor of MNK1 with enzyme IC50 of 40 nM at 2 mM ATP. |
| PC-62742 |
SEL-201
|
SEL-201 (SLV-2436, SEL201-88) is a novel potent, selective, ATP-competitive and oral MNK1/2 inhibitor with IC5010.8/5.4 nM, respectively. |
| PC-61145 |
MNK inhibitor 9
|
MNK inhibitor 9 is a potent, selective MAPK-interacting kinase (MNK1 and MNK2) inhibitor with IC50 of 3 nM for both, with no activity aginst CDK1/2 (IC50>25 uM). |
| PC-42035 |
eFT508
|
eFT508 (Tomivosertib) is a potent, highly selective, reversible, ATP-competitive, and orally bioavailable MNK1 and MNK2 inhibitor with IC50 of 1-2 nM in enzyme assays. |
| PC-38906 |
CID661578
|
CID661578 is a potent inducer of β-cell regeneration, targets MAP kinase-interacting serine/threonine kinase 2 (MNK2). |
