| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-49434 |
DR-1-55
|
|
DR-1-55 (DR-155) is a selective STAT3 inhibitor that covalently modifies a cysteine in the SH2 domain of STAT3. |
| PC-35089 |
PM-43I
|
1637532-77-4 |
PM-43I is a selective inhibitor of STAT5/6 Src Homology 2 (SH2) domain, binds recombinant STAT6 and STAT5B (IC50=1.8 and 3.8 uM) with much lower affinity for STAT3 (IC50=29.9 uM). |
| PC-62520 |
NSC 370284
|
116409-29-1 |
NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo. |
| PC-62519 |
UC-514321
|
299420-83-0 |
UC-514321 is a more effective analog of NSC-370284 that directly binds to STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo. |
| PC-62377 |
InS3-54A18
|
328998-53-4 |
InS3-54A18 is an active analog of inS3-54 targeting the DBD of STAT3 with IC50 of 8.8 uM in STAT3-dependent luciferase reporter assay, with increased specificity and pharmacological properties. |
| PC-61668 |
FLLL-32
|
1226895-15-3 |
FLLL-32 is a cell-permeable analog of curcumin that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50=5 uM). |
| PC-61628 |
STAT5b inhibitor 7
|
1818390-58-7 |
STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM. |
