Request The Product List ofApelin Receptor (APLNR)
Apelin Receptor (APLNR)
Apelin is an endogenous ligand of G protein-coupled receptor APJ. Apelin/APJ system is widely expressed in abundant tissues, especially bone, joint and muscle tissue.
Apelin and apelin receptors are expressed in many tissues and organ to regulate their physiological functions. Studies have shown that Apelin/apelin-receptor also expressed in ovary such as follicles, granulosa cells. Furthermore, Apelin/apelin-receptor play roles in vascular establishment and hormone metabolism in ovary.
The apelin receptor (APJ) is a member of the family A of G-protein-coupled receptors (GPCRs) and is involved in range of physiological and pathological functions, including fluid homeostasis, anxiety, and depression, as well as cardiovascular and metabolic disorders.
Therefore, drugs targeting apelin/APJ system undoubtedly provide more therapeutic options, ProbecChem prvided chemical tools for signaling pathways associated with apelin/APJ system.
1, Nigel A. Chapman, et al. Biochem Cell Biol. 2014 Dec; 92(6): 431-440.
2, Gonghui Hu, et al. Front Physiol. 2021 Feb 10;12:632886.