You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Histone Demethylase

Request The Product List ofHistone Demethylase Histone Demethylase

Cat. No. Product Name CAS No. Information
PC-36169

FB23-2

2243736-45-8 FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM.
PC-35471

Vafidemstat

1357362-02-7 Vafidemstat (ORY-2001, ORY2001) is a potent, selective, brain penetrant dual lysine-specific histone demethylase (LSD1, KDM1A)/MAO-B inhibitor with IC50 of 105 nM (KDM1A) and 58 nM (MAO-B).
PC-43206

ORY-1001 trans and cis isomers

1431326-61-2 ORY-1001 (RG-6016) is a highly potent, selective inhibitor of lysine-specific demethylase KDM1A (LSD1) with IC50 of 18 nM, displays high selectivity for KDM1A over other FAD-containing monoamine oxidases.
PC-62293

GS-5801

1596348-32-1 KDM5-C70 (GS-5801) is a cell-permeable derivative of KDM5-C49 (GS-080), potent, selective and cell permeable KDM5 inhibitor with IC50 of 0.3, 0.3 and 0.58 uM for KDM5A, B and C, respectively.
PC-61739

QC-6352

1851373-36-8 QC-6352 is a potent and selective KDM4 family inhibitor with IC50 of 104, 56, 35, and 104 nM for KDM4A, KDM4B, KDM4C, and KDM4D, respectively.
PC-61398

Seclidemstat

1423715-37-0 Seclidemstat (SP-2577, SP2577) is a potent, selective LSD1 inhibitor with IC50 of 127 nM.
PC-70332

SD-70

332173-89-4 SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com