| Cat. No. |
Product Name |
Information |
| PC-20353 |
CBA-1
|
CBA-1 is a small molecule inhibitor of Wnt signaling, specifically targets Jumonji (JmjC) domain-containing demethylase KDM3A with IC50 of 3.9 uM. |
| PC-49244 |
iJMJD6
|
iJMJD6 is a potent, specific small-molecule JMJD6 inhibitor that specifically binds to JMJD6 (ITC Kd=3.83 uM) and competes with α-KG and the substrate for binding, inhibits the demethylase activity of JMJD6 with IC50 of 149.6 nM. |
| PC-72385 |
FTO inhibitor CS1
|
FTO inhibitor CS1 (NSC 337766) is a potent, selective small-molecule inhibitor of m6A demethylase FTO, inhibits m6A demethylation with IC50 of 142.6 nM in vitro (cell-free) assays. |
| PC-72259 |
TACH101
|
TACH101 (Zavondemstat, QC8222, TACH 101) is a reversible, α-ketoglutarate competitive, selective and potent inhibitor of KDM4 isoforms A-D with IC50 values of 80 nM against all four isoforms. |
| PC-72226 |
FTO-04
|
FTO-04 is a potent, selective, competitive small molecule inhibitor of m6A-RNA demethylase FTO with IC50 of 3.39 uM, 13-fold selectivity over RNA demethylase ALKBH5 (ALKBH5, IC50=39.4 uM). |
| PC-38256 |
ALKBH5 inhibitor 6
|
ALKBH5 inhibitor 6 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 1.79 uM. |
| PC-38255 |
ALKBH5 inhibitor 3
|
ALKBH5 inhibitor 3 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 0.84 uM. |
