| Cat. No. |
Product Name |
Information |
| PC-23411 |
DXL-A-24
CaMKIIα inhibitor
|
DXL-A-24 is a spirocyclopiperazinium salt compound with antinociceptive effect, alleviates neuropathic pain by inhibiting CGRP expression, inhibits CaMKIIα phosphorylation. |
| PC-21505 |
SMP-114
CaMKII inhibitor
|
SMP-114 (Rimacalib) is a potent, specific and orally available CaMKII inhibitor with potential for treatment of rheumatoid arthritis. |
| PC-21443 |
CC-8977
CaMKK2 inhibitor
|
CC-8977 (CaMKK2-IN-1) is a hgihly potent, selective inhibitor of calcium/calmodulin-dependent kinase kinase II (CaMKK2) with binding IC50 of 7 nM. |
| PC-49624 |
SGC-CAMKK2-1N
|
SGC-CAMKK2-1N is the negative control compound of the CaMKK2 inhibitor SGC-CAMKK2-1 (Catalog# PC-49623), shows significantly less potent with CAMKK2 (IC50=27 uM). |
| PC-49623 |
SGC-CAMKK2-1
CaMKK2 inhibitor
|
SGC-CAMKK2-1 is a potent, selective chemical probe inhibitor that targets CaMKK2 with enzyme IC50 of 30 nM. |
| PC-49436 |
NCS-382
GHBR inhibitor
|
NCS-382 is a a gamma-hydroxybutyrate receptor (GHBR) antagonist, brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain, possesses antagonistic properties. |
| PC-49435 |
Ph-HTBA
CaMKIIα hub ligand
|
Ph-HTBA is a mid-nanomolar affinity (Ki=78nM), brain permeable ligand of CaMKIIα hub domain binding site. |
| PC-72972 |
AS105
CaMKII inhibitor
|
AS105 (AS-105) is a highly potent, ATP-competitive CaMKII inhibitor, inhibits CaMKIIδ with IC50 of 8 nM, Ki of 3 nM. |
| PC-72971 |
GS-680
CaMKII inhibitor
|
GS-680 (GS680) is a novel selective and ATP-competitive CaMKII inhibitor with biochemical IC50 of 2.3 and 15.9 nM against CaMKIIδ and CaMKIIα, respectively. |
| PC-72970 |
RA608
CaMKII inhibitor
|
RA608 (RA-608) is a potent, selective, ATP-competitive, orally available CaMKII inhibitor, inhibits human CaMKIIδ, CaMKIIɣ, CaMKIIα, and CaMKIIβ with IC50 of 22, 51, 121, and 1135 nM, respectively. |
| PC-72969 |
RA306
CaMKII inhibitor
|
RA306 (RA-306) is a selective, potent, orally active, ATP-competitive CaMKII inhibitor, inhibits CaMKII delta (IC50=15 nM), gamma (IC50=25 nM), and alpha (IC50=61 nM) isoforms. |
| PC-72949 |
TIM-063
CaMKK inhibitor
|
TIM-063 (TIM063) is a potent, selective, ATP-competitive CaMKK inhibitor with Ki of 0.35/0.2 uM for CaMKKα and CaMKKβ, respectively. |
