| Cat. No. |
Product Name |
Information |
| PC-20292 |
OICR-8268
|
OICR-8268 (OICR8268) is a highly potent, reversible, small molecule ligand of DCAF1 (Vpr binding protein) with SPR KD of 38 nM, a substrate receptor of two distinct E3 ligases (CRL4DCAF1 and EDVP). |
| PC-49196 |
BC18630 free base
|
BC18630 free base (BC 18630) is a small molecule inhibitor of the E3 ubiquitin ligase subunit DCAF7, potently inhibits SARS-CoV-2 infection with IC50 of 39 nM in cell-based assays. |
| PC-49194 |
BC18813
|
BC18813 (BC 18813) is a small molecule inhibitor of the E3 ubiquitin ligase subunit DCAF7, potently inhibits SARS-CoV-2 infection with IC50 of 48 nM in cell-based assays. |
| PC-49193 |
BC18630
|
BC18630 (BC 18630) is a small molecule inhibitor of the E3 ubiquitin ligase subunit DCAF7, potently inhibits SARS-CoV-2 infection with IC50 of 39 nM in cell-based assays. |
| PC-72861 |
BIO-2007817
|
BIO-2007817 is a small-molecule positive allosteric modulator of Parkin E3 ligase with EC50 of 0.17 uM (TR-FRET). |
| PC-72548 |
KH-4-43
|
KH-4-43 is a small moelcule E3 CRL4 inhibitor and exhibits antitumor potential, directly and selectively binds to the purified E3 ROC1-CUL4A CTD complex with Kd of 83 nM. |
| PC-72478 |
BC1618
|
BC1618 (BC-1618) a novel inhibitor of orphan ubiquitin E3 ligase subunit protein Fbxo48, interrupts Fbxo48/pAmpkα interaction and increases pAmpkα levels. |
