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Cat. No. Product Name CAS No. Information
PC-72321

BRD8 inhibitor DN02

BRD8 inhibitor DN02 is a first-in-class selective and cellularly active probe for NuA4 factor BRD8 (BD1) with AlphaScreen IC50 of 48 nM, and Kd of 34 nM, displays IC50 of 0.64 uM in-cell engagement within BRET displacement assays, shows no affinity for BRD8 (BD2), CBP, and p300 (IC50>10 uM).
PC-38148

Alobresib

1637771-14-2 GS-5829 (GS5829, Alobresib) is a novel potent, selective BET inhibitor.
PC-38071

GSK778

2451862-42-1 GSK778 is a potent and selective inhibitor of bromodomain (BRD) BD1 with IC50 of 75 nM (BRD2-BD1), 41 nM (BRD3-BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively.
PC-38064

ODM-207

1801503-93-4 ODM-207 (ODM207) is a highly potent, selective and orally active pan-BET inhibitor with potent and broad antiproliferative effects.
PC-35848

TP-238

2415263-04-4 TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30 nM against CECR2 and 350 nM against BPTF in an alphascreen assay, KD of 10 nM for CECR2 and 120nM for BPTF in ITC assays.
PC-35172

ABBV-744

2138861-99-9 ABBV-744 (ABBV744) is a highly potent and selective inhibitor of the BD2 domain of BET family proteins with IC50 of 4-18 nM for BD2 of BRD2, BRD3, BRD4 and BRDT.
PC-35097

ZL0454

2229042-77-5 ZL0454 is a potent, highly selective small-molecule BRD4 inhibitor with IC50 of 49 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively.

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