| Cat. No. |
Product Name |
Information |
| PC-28081 |
Beta-caryophyllene
CB2 agonist
|
Beta-caryophyllene (β-Caryophyllene, (E)-BCP) is a high affinity, selective agonist of cannabinoid receptor type 2 (CB2) with Ki of 115 nM, also possesses significant anticancer activities, affecting growth and proliferation of numerous cancer cells. |
| PC-27725 |
RTICBM-303
CB1 NAM
|
RTICBM-303 is a potent, selective negative allosteric modulator (NAM) of CB1 receptor with pIC50 of 7.07 in Ca2+ assays. |
| PC-25525 |
BI-5756
CETP inhibitor, CB1 agonist
|
BI-5756 is a cholesteryl ester transfer protein (CETP) inhibitor, also is a potent agonist of cannabinoid receptor 1 (CB1R, CB1) with IC50 of 0.966 uM in cell-based radioligand binding assay using CP55940. |
| PC-22602 |
RNB-61
CB2R agonist
|
RNB-61 is a highly potent, selective and orally bioavailable cannabinoid CB2 receptor (CB2R) full agonist with Ki of 0.57/1.33 nM for hCB2R/mCB2R, >5000-fold selective over hCB1R. |
| PC-22234 |
HU-308
CB2 agonist
|
HU-308 is a potent, selective cannabinoid CB2 receptor agonist with Ki of 22.7 nM in competition binding assay, does not bind to CB1 receptor. |
| PC-22188 |
SR141716
CB1 antagonist
|
Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with Ki of 1.8 nM, no affinity for peripheral cannabinoid receptor. |
| PC-21521 |
AM4113
CB1 neutral antagonist
|
AM4113 is a high affinity, selective cannabinoid CB1 neutral antagonist with Ki of 0.89 nM, exhibits 100-fold selectivity over CB2 receptors. |
| PC-21463 |
AM6527
CB1 antagonist
|
AM6527 is a highly potent, selective cannabinoid CB1 receptor antagonist with binding Ki of 4.88 nM, 100-fold selective over CB2 receptors. |
| PC-21437 |
JWH133
CB2 agonist
|
JWH133 (JWH-133) is a potent and selective CB2 agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors, inhibits glioma growth in vivo. |
| PC-21217 |
O-1918
GPR18 antagonist
|
O-1918 is a selective, potent antagonist of non-canonical cannabinoid GPR18, does not bind to CB(1) or CB(2) receptors and does not cause vasorelaxation at concentrations up to 30 uM. |
| PC-21097 |
PSB-KK1415
GPR18 agonist
|
PSB-KK1415 is a selective GPR18 agonist with EC50 of 19.1 nM (hGPR18) in β-arrestin recruitment assays, shows no activity against GPR55. |
| PC-21096 |
PSB-KD477
GPR18 agonist
|
PSB-KD477 is a potent, selective GPR18 agonist with EC50 of 454 nM, shows no activity against GPR55. |
