| Cat. No. |
Product Name |
Information |
| PC-28432 |
MRS1220
A3AR antagonist
|
MRS1220 is a highly potent and selective A3 adenosine receptor (A3AR) antagonist with Ki of 0.59 nM for hA3AR. |
| PC-28428 |
MRS1523
A3AR antagonist
|
MRS1523 (MRS 1523) is a potent and selective adenosine A3 receptor (A3AR) antagonist with Ki of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. |
| PC-28427 |
DPTN dihydrochloride
A3AR antagonist
|
DPTN dihydrochloride (MRS7799) is a potent and selective A3 adenosine receptor (A3AR) antagonist with of 1.65, 9.61, and 8.53 nM for human, mouse, and rat A3AR respectively, and EC50 of 63.8 nM in A3AR-βarr2 recruitment assay. |
| PC-28050 |
Muvadenant fumarate
Adenosine A2A/A2B inhibitor
|
Muvadenant fumarate (M1069) is a potent, orally active dual antagonist of the A2A and A2B adenosine receptors, with selectivity of >100 fold against the A1 and A3 receptors. |
| PC-27083 |
JNJ-10450232
A3AR agonist
|
JNJ-10450232 (NTM-006) is a structural analog of acetaminophen, non-opioid, non-NSAID analgesic and antipyretic compound, demonstrates anti-pyretic and/or analgesic activities, NTM-006 is a selective adenosine A3 receptor (A3AR) agonist. |
| PC-26707 |
MK-1088
A2AR/A2BR antagonist
|
MK-1088 is a potent, selective dual adenosine A2A receptor (A2AR) and A2B receptor (A2BR) antagonist with Ki values of 0.31 nM and 5.3 nM for human A2AR and A2BR respectively. |
| PC-25759 |
P626
A2AR/A2BR antagonist
|
P626 is a potent, selective dual adenosine A2A/A2B receptor (A2AR/A2BR) antagonist with IC50 of 5.73 nM and 34 nM at both hA2AAR and hA2BAR (cAMP assay), with no significant acitivity against hA1AR and hA3AR. |
| PC-23909 |
FM101
A3AR inhibitor
|
FM101 (LJ-2698) is a highly potent and selective antagonist of A3 adenosine receptor (A3AR), selectively binds to human A3AR with Ki of 1.44 nM. |
| PC-23389 |
SLV320
A1AR antagonist
|
Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor (A1AR) antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. |
| PC-22840 |
DPCPX
A1AR antagonist
|
DPCPX (PD116948) is a highly potent and selective adenosine A1 receptor antagonist with Ki of 0.46 nM, >500-fold selective over A2 receptor. |
| PC-22753 |
MRS-1706
A2BR antagonist
|
MRS-1706 (MRS1706) is a potent and selective adenosine A2B receptor (A2BR) inverse agonist / antagonist with Ki of 1.39 nM, >100-fold selective over A2A, A1 and A3 receptors. |
| PC-22524 |
MRS1754
A2BR antagonist
|
MRS1754 (MRS-1754) is a potent, adenosine receptor A2B adenosine receptor (A2BAR) selective antagonist with Ki of 1.97 nM, 205-, 255-, and 289-fold selective for the human A2BARs vs. human A1/A2A/A3 ARs, respectively. |
