| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35541 |
DRAinh-A250
|
858747-13-4 |
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
| PC-60024 |
CLP257
|
1181081-71-9 |
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM. |
| PC-49192 |
TMEM16A blocker 1PBC
|
362602-12-8 |
1PBC is a small molecule blocker of calcium-activated chloride channel TMEM16A, blocks TMEM16A completely with an IC50 of 4 uM at zero mV and saturating Ca2+ concentration (2 uM). |
| PC-47048 |
TMinh-23
|
2098490-06-1 |
TMinh-23 is (Compound 10bm) is a potent, selective inhibitor of transmembrane protein 16A (TMEM16A or ANO1, DOG1, ORAOV2, TAOS-2) with IC50 of 30 nM in short-circuit current assays, weakly inhibits TMEM16B (IC50=400 nM, 13 -fold selectivity). |
| PC-38752 |
DRAinh-A270
|
858753-48-7 |
DRAinh-A270 is a small-molecule, selective inhibitor of intestinal anion exchanger SLC26A3 (DRA), inhibits SLC26A3-mediated chloride/bicarbonate exchange with IC50 of 35 nM and oxalate/chloride exchange with IC50 of 60 nM. |
| PC-38691 |
VI-116
|
1380411-59-5 |
VI-116 is a potent and selective volume-regulated anion channel (VRAC) inhibitor, fully inhibits VRAC-mediated I- quenching with an IC50 of 1.27 uM in LN215 cells. |
| PC-38479 |
MONNA
|
1572936-83-4 |
MONNA a potent, selective inhibitor of the TMEM16A calcium-activated chloride channel (Anoctamin-1, ANO1) with IC50 of 80 nM (xANO1). |
