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Cat. No. Product Name Information
PC-62399

Dynarrestin

Dynein inhibitor

Dynarrestin is a novel inhibitor of cytoplasmic Dyneins 1 and 2, acts reversibly to inhibit cytoplasmic dynein 1-dependent microtubule binding and motility in vitro without affecting ATP hydrolysis.
PC-62398

Ciliobrevin D

Dynein inhibitor

Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of AAA+ ATPase cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking.
PC-62397

Dynein2-IN-37

Dynein 2 inhibitor

Dynein2-IN-37 (Ciliobrevin analog 37) is a potent, selective cytoplasmic dynein 2 ATPase activity antagonist with IC50 of 11 uM, shows weak inhibition for dynein 2 (IC50=280 uM).
PC-42258

Ciliobrevin A

Hedgehog inhibitor, Dynein inhibitor

Ciliobrevin A (HPI-4) is a small molecule Hedgehog pathway inhibitor (IC50=7 uM) that acts downstream of Su(fu) to modulate Gli processing, activation or trafficking, inhibits AAA+ ATPase motor cytoplasmic dynein.

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