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Chemical Structure : 1-ABC
CAS No.: 50892-83-6
Catalog No.: PC-73392Not For Human Use, Lab Use Only.
1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $248 | In stock | |
| 100 mg | $548 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
Single amino acid substitutions in the putative phosphatase Oca6 and in the transcription factor Rob1 could bypass the filamentation-repressive effects of 1-ABC.
| M.Wt | 210.236 | |
| Formula | C13H10N2O | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. MacAlpine J, et al. Nat Commun. 2021 Oct 22;12(1):6151.
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