Catalog No.: PC-28016Not For Human Use, Lab Use Only.
10-Shogaol ([10]-Shogaol) is an active component of steamed ginger increases adrenaline secretion via the activation of TRPV1, also partially activates 5-HT1A receptor with Ki of 3-20 uM, also inhibits PMA-stimulated MDA-MB-231 cell invasion by reducing MMP-9 expression, also inhibits COX-2 with IC50 of 7.5 uM.
10-Shogaol ([10]-Shogaol) is an active component of steamed ginger increases adrenaline secretion via the activation of TRPV1, also partially activates 5-HT1A receptor with Ki of 3-20 uM, also inhibits PMA-stimulated MDA-MB-231 cell invasion by reducing MMP-9 expression, also inhibits COX-2 with IC50 of 7.5 uM.
Physicochemical Properties
M.Wt
332.48
Formula
C21H32O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-(4-Hydroxy-3-methoxyphenyl)tetradec-4-en-3-one
References
1. Nievergelt A, et al. Bioorg Med Chem. 2010 May 1;18(9):3345-51.
2. Iwasaki Y, et al. Nutr Neurosci. 2006 Jun-Aug;9(3-4):169-78.
3. Ling H, et al. Br J Pharmacol. 2010 Dec;161(8):1763-77.
4. van Breemen RB, et al. Fitoterapia. 2011 Jan;82(1):38-43.
