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10074-G5

Chemical Structure : 10074-G5

CAS No.: 413611-93-5

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10074-G5 (10074G5)

Catalog No.: PC-42299Not For Human Use, Lab Use Only.

10074-G5 is a small molecules that disrupts c-Myc-Max heterodimerization, binds to and distorts the bHLH-ZIP domain of c-Myc.

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10 mg $78 In stock
25 mg $128 In stock
50 mg $218 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

10074-G5 is a small molecules that disrupts c-Myc-Max heterodimerization, binds to and distorts the bHLH-ZIP domain of c-Myc.
10074-G5 inhibits the growth of Daudi Burkitt's lymphoma cells and disrupts c-Myc/Max dimerization.

Physicochemical Properties

M.Wt 332.31288
Formula C18H12N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 28 mg/mL
Chemical Name/SMILES

2,1,3-Benzoxadiazol-4-amine, N-[1,1'-biphenyl]-2-yl-7-nitro-

References

1. Follis AV, et al. Chem Biol. 2008 Nov 24;15(11):1149-55.

2. Clausen DM, et al. J Pharmacol Exp Ther. 2010 Dec;335(3):715-27.

3. Hammoudeh DI, et al. J Am Chem Soc. 2009 Jun 3;131(21):7390-401.

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