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Chemical Structure : 2-APB
CAS No.: 524-95-8
Catalog No.: PC-60019Not For Human Use, Lab Use Only.
2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $78 | In stock | |
| 100 mg | $128 | In stock | |
| 250 mg | $198 | In stock | |
| 1 g | Get quote |
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2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker.
2-APB stimulates store-operated calcium (SOC) release at 10 uM,.
2-APB ncreases STIM-Orai channel conductance and limits ion selectivity.
| M.Wt | 225.094 | |
| Formula | C14H16BNO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in DMSO |
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| Chemical Name/SMILES |
2-Aminoethoxydiphenylborane |
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1. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5.
2. Maruyama T, et al. J Biochem. 1997 Sep;122(3):498-505.
3. Bai D, et al. J Pharmacol Exp Ther. 2006 Dec;319(3):1452-8.
4. Togashi K, et al. Br J Pharmacol. 2008 Mar;153(6):1324-30.
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