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3-Bromo-7-Nitroindazole

Chemical Structure : 3-Bromo-7-Nitroindazole

CAS No.: 74209-34-0

3-Bromo-7-Nitroindazole

Catalog No.: PC-35420Not For Human Use, Lab Use Only.

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM.

Physicochemical Properties

M.Wt 242.032
Formula C7H4BrN3O2
CAS No. 74209-34-0
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name

3-bromo-7-nitro-1H-indazole

References

1. Gammie SC, et al. Brain Res. 2000 Jul 7;870(1-2):80-6.

2. Gocmez SS, et al. Pharmacol Biochem Behav. 2015 Apr;131:19-25.

3. Widdowson PS, et al. Br J Pharmacol. 1996 Apr;117(8):1761-7.

4. Vaupel DB, et al. Eur J Pharmacol. 1997 Apr 11;324(1):11-20.

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