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Chemical Structure : 4-IBP
CAS No.: 155798-08-6
Catalog No.: PC-42070Not For Human Use, Lab Use Only.
4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $80 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively.
4-IBP decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
| M.Wt | 420.2873 | |
| Formula | C19H21IN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzamide, 4-iodo-N-[1-(phenylmethyl)-4-piperidinyl]- |
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1. John CS, et al. Cancer Res. 1995 Jul 15;55(14):3022-7.
2. Bermack JE, et al. Br J Pharmacol. 2001 Oct;134(3):691-9.
3. Mégalizzi V, et al. Neoplasia. 2007 May;9(5):358-69.
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