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5-Azacytidine

Chemical Structure : 5-Azacytidine

CAS No.: 320-67-2

5-Azacytidine (Ladakamycin;5-AzaC;Azacitidine)

Catalog No.: PC-42672Not For Human Use, Lab Use Only.

A chemical analog of Cytidine that inhibits DNA methyltransferase.

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Biological Activity

A chemical analog of Cytidine that inhibits DNA methyltransferase; induces mitochondrial apoptosis and autophagy.

Chemotherapeutic Agents

Approved

Physicochemical Properties

M.Wt 244.2047
Formula C8H12N4O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL

Chemical Name/SMILES

1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-ribofuranosyl-

References

1. Cluzeau T, et al. Cell Cycle. 2011 Jul 15;10(14):2339-43.

2. Flotho C, et al. Leukemia. 2009 Jun;23(6):1019-28.

3. Tobiasson M, et al. Oncotarget. 2017 Apr 25;8(17):28812-28825.

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