Catalog No.: PC-28015Not For Human Use, Lab Use Only.
6-Shogaol ([6]-Shogaol) is an active compound isolated from ginger root (Rhizoma Zingiberis Recens) with various biological activities including anticancer, anti-inflammation, and anti-oxidation, inhibits breast and colon cancer cell proliferation through activation of PPARγ.
6-Shogaol ([6]-Shogaol) is an active compound isolated from ginger root (Rhizoma Zingiberis Recens) with various biological activities including anticancer, anti-inflammation, and anti-oxidation, inhibits breast and colon cancer cell proliferation through activation of PPARγ.
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor gamma (PPARgamma).
6-Shogaol inhibits PMA-stimulated MDA-MB-231 cell invasion with an accompanying decrease in MMP-9 secretion, decreases NF-κB transcriptional activity.
6-shogaol induces apoptosis, modulates cyclins expression and targets cancer survival signaling pathways in HCC cell lines.
Physicochemical Properties
M.Wt
276.38
Formula
C17H24O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-(4-Hydroxy-3-methoxyphenyl)dec-4-en-3-one
References
1. Tan BS, et al. Cancer Lett. 2013 Aug 9;336(1):127-39.
2. Zuo F, et al. Phytomedicine. 2026 Oct;160:158594.
3. Xu X, et al. Phytomedicine. 2026 Sep;159:158541.
4. Ling H, et al. Br J Pharmacol. 2010 Dec;161(8):1763-77.
