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6H05 trifluoroacetate

Chemical Structure : 6H05 trifluoroacetate

CAS No.: 2061344-88-3

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6H05 trifluoroacetate (K-Ras inhibitor, 6H05 TFA)

Catalog No.: PC-43022Not For Human Use, Lab Use Only.

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.

Physicochemical Properties

M.Wt 590.1425
Formula C22H31ClF3N3O4S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 51 mg/mL
Chemical Name/SMILES

4-Piperidinecarboxamide, 1-[2-[(4-chlorophenyl)thio]acetyl]-N-[2-[[2-(dimethylamino)ethyl]dithio]ethyl]-, 2,2,2-trifluoroacetic acid

References

1. Ostrem JM, et al. Nature. 2013 Nov 28;503(7477):548-51.

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