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Chemical Structure : 6K465
Catalog No.: PC-22139Not For Human Use, Lab Use Only.
6K465 is a potent selective Aurora A (AURKA) inhibitor, effectively inhibits cancer cells overexpressing c-MYC- and/or N-MYC.
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6K465 is a potent selective Aurora A (AURKA) inhibitor, effectively inhibits cancer cells overexpressing c-MYC- and/or N-MYC.
6K465 reduces levels of c-MYC and N-MYC oncoproteins more potently than alisertib.
6K465 dispalys potent antiproliferative effect an sensitivity against cell lung cancer (SCLC) and breast cancer (BC) cell lines with high protein levels of c-MYC and/or N-MYC.
| M.Wt | 542.05 | |
| Formula | C26H33ClFN9O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chang CP, et al. Mol Cancer Ther. 2024 Apr 9. doi: 10.1158/1535-7163.MCT-23-0602.
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