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710GO

Chemical Structure : 710GO

CAS No.: 3097898-48-8

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710GO (EMBC-710GO)

Catalog No.: PC-26943Not For Human Use, Lab Use Only.

710GO (EMBC-710GO) is a potent, selective, orally available melanocortin receptor MC3R/MC4R dual agonist with EC50 of 0.073/0.042 nM respectively in cAMP signaling assays, induces significant weight loss in primates with diet-induced obesity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    710GO (EMBC-710GO) is a potent, selective, orally available melanocortin receptor MC3R/MC4R dual agonist with EC50 of 0.073/0.042 nM respectively in cAMP signaling assays, induces significant weight loss in primates with diet-induced obesity.

    Physicochemical Properties

    M.Wt 1238.44
    Formula C60H84FN17O11
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2S,5R,8S,11S,14S,22S)-2-((1H-imidazol-4-yl)methyl)-11-((1H-indol-3-yl)methyl)-22-((S)-2-acetamidohexanamido)-N-((R)-1-((R)-2-carbamoylpyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-8-(3-((diaminomethylene)amino)propyl)-5-(4-fluorobenzyl)-3,6,9,12,19,23-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-14-carboxamide

    References

    1. Seiler JL, et al. Nat Commun. 2026 May 29;17(1):4808.

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