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8-Nitrotryptanthrin

Chemical Structure : 8-Nitrotryptanthrin

CAS No.: 77603-42-0

8-Nitrotryptanthrin

Catalog No.: PC-42226Not For Human Use, Lab Use Only.

A potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM.

Physicochemical Properties

M.Wt 293.2338
Formula C15H7N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 6.4 mg/mL (Need warming)

Chemical Name/SMILES

Indolo[2,1-b]quinazoline-6,12-dione, 8-nitro-

References

1. Li J, et al. Eur J Med Chem. 2016 Nov 10;123:171-179.

2. Scovill J, et al. Antimicrob Agents Chemother. 2002 Mar;46(3):882-3.

3. Hwang JM, et al. J Nat Prod. 2013 Mar 22;76(3):354-67.

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