You are here:Home-Chemical Inhibitors & Agonists-TGF-beta/Smad-TGF beta Receptor (TGFBR)-A 77-01
A 77-01

Chemical Structure : A 77-01

CAS No.: 607737-87-1

A 77-01 (A77-01;A-77-01)

Catalog No.: PC-45993Not For Human Use, Lab Use Only.

A potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.

Packing Price Stock Quantity
10 mg $144 In stock
50 mg $455 In stock

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM; A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01.

Physicochemical Properties

M.Wt 286.3306
Formula C18H14N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-

References

1. Tojo M, et al. Cancer Sci. 2005 Nov;96(11):791-800.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: