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Chemical Structure : AAL-149
Catalog No.: PC-21131Not For Human Use, Lab Use Only.
AAL-149 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 1.081 uM, shows potent anti-inflammatory effects in vivo.
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AAL-149 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 1.081 uM, shows potent anti-inflammatory effects in vivo.
AAL-149 inhibit LPS-induced inflammatory gene expression in macrophages and microglia.
| M.Wt | 293.45 | |
| Formula | C18H31NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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