ABD0171 | ALDH1A3 inhibitor | Probechem Biochemicals

Chemical Structure : ABD0171

ABD0171 (ABD-0171)

Catalog No.: PC-25912Not For Human Use, Lab Use Only.

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

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Biological Activity

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

Physicochemical Properties

M.Wt	333.49
Formula	C19H27NO2S:
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pentynethioic acid, 4-[[2-[(3,4-dimethylphenyl)methoxy]ethyl]methylamino]-4-methyl-, S-methyl ester

References

1. Pequerul R, et al. Cell Chem Biol. 2025 Oct 16;32(10):1260-1278.e12.

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ABD0171 (ABD-0171)

Biological Activity

Physicochemical Properties

References

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