Pimicotinib (ABSK021) | CSF1R inhibitor

Chemical Structure : ABSK021

CAS No.: 2253123-16-7

ABSK021 (Pimicotinib, ABSK-021)

Catalog No.: PC-22914Not For Human Use, Lab Use Only.

Pimicotinib (ABSK021) is a highly potent and selective, orally active inhibitor of CSF-1R with IC50 of 19.48 nM, shows significant pre-clinical anti-tumor activity.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

Pimicotinib (ABSK021) is a highly potent and selective, orally active inhibitor of CSF-1R with IC50 of 19.48 nM, shows significant pre-clinical anti-tumor activity.

Physicochemical Properties

M.Wt	420.47
Formula	C22H24N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3,3-Dimethyl-N-(6-methyl-5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)-2-oxopyrrolidine-1-carboxamide

References

1. Zhixuan Zhu, et al. Cancer Res (2022) 82 (12_Supplement): LB513.

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ABSK021 (Pimicotinib, ABSK-021)

Biological Activity

Physicochemical Properties

References

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