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Chemical Structure : ABT-724
CAS No.: 70006-24-5
Catalog No.: PC-70061Not For Human Use, Lab Use Only.
A potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ABT-724 is a potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors.
ABT-724 elicits penile erections in rats at a dose of 0.03 uMl/kg, increases intracavernosal pressure in awake freely moving rats.
| M.Wt | 293.366 | |
| Formula | C17H19N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole |
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1. Brioni JD, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6758-63.
2. Cowart M, et al. J Med Chem. 2004 Jul 15;47(15):3853-64.
3. Yin P, et al. Neurosci Lett. 2014 Sep 19;580:142-6.
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