Vibilsertib (AC-003) | RIPK1 inhibitor

Chemical Structure : AC-003

AC-003 (Vibilsertib, AC003)

Catalog No.: PC-21572Not For Human Use, Lab Use Only.

Vibilsertib (AC-003) is a novel oral small-molecule inhibitor of receptor interacting protein kinase 1(RIPK1), inhibits necrosis and has the potential for treating idiopathic pulmonary fibrosis.

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Biological Activity

Vibilsertib (AC-003) is a novel oral small-molecule inhibitor of receptor interacting protein kinase 1(RIPK1), effectively inhibits RIPK1-mediated necrosis and has the potential for treating idiopathic pulmonary fibrosis.

Physicochemical Properties

M.Wt	463.49
Formula	C24H25N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	tetrahydro-2H-pyran-4-yl 7-(2-(cyclopropanecarboxamido)imidazo[1,2-a]pyridin-6-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate

References

1. Patent WO2018237370 A1 2018-12-27 (Compound B19).

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AC-003 (Vibilsertib, AC003)

Biological Activity

Physicochemical Properties

References

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