ACP-5862 (ACP5862)

Chemical Structure : ACP-5862

CAS No.: 2230757-47-6

Catalog No.: PC-49426Not For Human Use, Lab Use Only.

ACP-5862 (ACP5862) is a major metabolite of acalabrutinib and potent and selective covalent BTK inhibitor with IC50 of 5 nM.

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Biological Activity

ACP-5862 (ACP5862) is a major metabolite of acalabrutinib and potent and selective covalent BTK inhibitor with IC50 of 5 nM.

M.Wt	481.516
Formula	C26H23N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(8-amino-3-(4-(but-2-ynamido)butanoyl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

1. Terry Podoll, et al. J Pharmacol Exp Ther. 2022 Oct 30;JPET-AR-2022-001116.