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Chemical Structure : ADAM9i
Catalog No.: PC-21808Not For Human Use, Lab Use Only.
ADAM9i is a specific small molecule inhibitor of ADAM9 protein with binding KD of 5.9 uM and enzyme IC50 of 5.2 uM, promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy.
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ADAM9i is a specific small molecule inhibitor of ADAM9 protein with binding KD of 5.9 uM and enzyme IC50 of 5.2 uM, promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy.
| M.Wt | 529.59 | |
| Formula | C26H19N5O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yu-Kai Huang, et al. Nat Cancer. 2024 Jan 24. doi: 10.1038/s43018-023-00720-x.
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