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ADU-S100

Chemical Structure : ADU-S100

CAS No.: 1638750-95-4

ADU-S100 (MIW815)

Catalog No.: PC-62639Not For Human Use, Lab Use Only.

ADU-S100 (MIW815) is a synthetic cyclic dinucleotide agonist of STING, elicits potent and durable anti-tumor immunity when administered IT in pre-clinical syngeneic tumor models..

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Biological Activity

ADU-S100 (MIW815) is a synthetic cyclic dinucleotide agonist of STING, elicits potent and durable anti-tumor immunity when administered IT in pre-clinical syngeneic tumor models.

Physicochemical Properties

M.Wt 734.5
Formula C20 H24 N10 O10 P2 S2 . 2 Na
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,5R,7R,8R,10R,12aR,14R,15R,15aS,16R)-7,14-Bis(6-amino-9H-purin-9-yl)-15,16-dihydroxy-2,10-dimercaptooctahydro-12H-5,8-methanofuro[3,2-l][1,3,6,9,11]pentaoxa[2,10]diphosphacyclotetradecine 2,10-dioxide disodium salt

References

1. Cancer Discov. 2018 Jan 25. doi: 10.1158/2159-8290.CD-ND2018-002.

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