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Chemical Structure : AGI-6780
CAS No.: 1432660-47-3
Catalog No.: PC-44670Not For Human Use, Lab Use Only.
AGI-6780 is a potent and selective mutant IDH2 R140Q inhibitor with IC50 of 23 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $528 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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AGI-6780 is a potent and selective mutant IDH2 R140Q inhibitor with IC50 of 23 nM.
AGI-6780 shows excellent selectivity against other dehydrogenases.
AGI-6780 induces differentiation of TF-1 erythroleukemia and primary human acute myelogenous leukemia cells in vitro.
| M.Wt | 481.5111 | |
| Formula | C21H18F3N3O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 29 mg/mL |
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| Chemical Name/SMILES |
Benzenesulfonamide, N-cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]- |
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1. Wang F, et al. Science. 2013 May 3;340(6132):622-6.
2. Kernytsky A, et al. Blood. 2015 Jan 8;125(2):296-303.
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