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AH 6809

Chemical Structure : AH 6809

CAS No.: 33458-93-4

AH 6809 (AH6809;AH-6809)

Catalog No.: PC-42574Not For Human Use, Lab Use Only.

A xanthone derivative that fuctions as an EP and DP receptor antagonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A xanthone derivative that fuctions as an EP and DP receptor antagonist; blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor; an effective antagonist antiaggregatory actions of PGD2, but not PGI2, with EC50 50 uM in whole human platelet.

Physicochemical Properties

M.Wt 298.2901
Formula C17H14O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-

References

1. Armstrong RA, et al. Br J Pharmacol. 1986 Mar;87(3):543-51.

2. Woodward DF, et al. Biochem Pharmacol. 1995 Nov 9;50(10):1731-3.

3. Keery RJ, et al. Br J Pharmacol. 1988 Jul;94(3):745-54.

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