AK-068 | STAT6 inhibitor | Probechem Biochemicals

Chemical Structure : AK-068

Catalog No.: PC-23177Not For Human Use, Lab Use Only.

AK-068 is a highly potent, selective STAT6 ligand / inhibitor with Ki of 6 nM, binds to STAT6 SH2 domain.

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Biological Activity

AK-068 is a highly potent, selective STAT6 ligand / inhibitor with Ki of 6 nM, binds to STAT6 SH2 domain.

M.Wt	663.67
Formula	C31H36F2N3O7PS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((2-(((S)-3,3-dimethyl-1-oxo-1-((S)-2-((R)-2-phenylmorpholine-4-carbonyl)pyrrolidin-1-yl)butan-2-yl)carbamoyl)benzo[b]thiophen-5-yl)difluoromethyl)phosphonic acid

1. Kaneshige A, et al. J Med Chem. 2024 Sep 23. doi: 10.1021/acs.jmedchem.4c01009.