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Chemical Structure : ALD1A3 inhibitor CB29
Catalog No.: PC-20206Not For Human Use, Lab Use Only.
ALD1A3 inhibitor CB29 is a selective small molecule inhibitor of ALDH3A1 with IC50 of 16 uM, and Ki value of 4.7 uM.
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ALD1A3 inhibitor CB29 is a selective small molecule inhibitor of ALDH3A1 with IC50 of 16 uM, and Ki value of 4.7 uM.
ALD1A3 inhibitor CB29 binds competitively to the aldehyde binding site.
ALD1A3 inhibitor CB29 exhibits good selectivity toward ALDH3A1, demonstrates no inhibition (<5%) toward ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1 or ALDH2 up to 250 μM.
ALD1A3 inhibitor CB29 can inhibit the activity of ALDH3A1 in tumor whole cell lysates.
ALD1A3 inhibitor CB29 is a chemical tool to delineate the role of ALDH3A1 in numerous metabolic pathway.
| M.Wt | 349.36 | |
| Formula | C15H15N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bibek Parajuli, et al. Chembiochem. 2014 Mar 21;15(5):701-12.
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